ACY-775

  • Chemical Properties
CAS No. 1375466-18-4 Cat. No. BCP30179
Name ACY-775
Synonyms ACY 775; ACY775;
Formula C17H19FN4O2 M. Wt 330.36
  • Biological Activity
Description ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-775 shares the antidepressant-like properties of other HDAC inhibitors, such as SAHA and MS-275, in the tail suspension test and social defeat paradigm.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets HDAC 

Structure

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