Aurora Kinase Inhibitor III
| CAS No. | 879127-16-9 | Cat. No. | BCP30248 |
| Name | Aurora Kinase Inhibitor III | ||
| Synonyms | |||
| Formula | C21H18F3N5O | M. Wt | 413.40 |
| Description | Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM). It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively). | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | Aurora | ||
Structure
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