BI-671800
| CAS No. | 1093108-50-9 | Cat. No. | BCP30656 |
| Name | BI-671800 | ||
| Synonyms | AP-761;AP761; AP 761;BI 671800; BI671800; | ||
| Formula | C25H26F3N5O3 | M. Wt | 501.50 |
| Description | BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Prostaglandin Receptor | ||
Structure
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