JBJ-04-125-02

  • Chemical Properties
CAS No. 2140807-05-0 Cat. No. BCP31914
Name JBJ-04-125-02
Synonyms 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide;
Formula C29H26FN5O3S M. Wt 543.62
  • Biological Activity
Description JBJ-04-125-02 is a single agent can inhibit cell proliferation and EGFRL858R/T790M/C797S signaling in vitro and in vivo.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR 

Structure

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