EGFR inhibitor

  • Chemical Properties
CAS No. 879127-07-8 Cat. No. BCP32602
Name EGFR inhibitor
Synonyms
Formula C21H18F3N5O M. Wt 413.4
  • Biological Activity
Description EGFR inhibitor is a cell permeable, 4,6-disubstituted pyrimidine compound that selectively inhibits the EGFR kinase with an IC50 value of 21 nM in vitro and blocks receptor autophosphorylation in cells.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR 

Structure

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