Indibulin
| CAS No. | 204205-90-3 | Cat. No. | BCP33949 |
| Name | Indibulin | ||
| Synonyms | ZIO 301;D 24851;ZIO301;D24851;ZIO-301;D-24851; | ||
| Formula | C22H16ClN3O2 | M. Wt | 389.83 |
| Description | Indibulin is a synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines. Check for active clinical trials or closed clinical trials using this agent. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Microtubule | ||
Structure
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