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Indibulin Chemical Structure

Indibulin

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP33949CAS No. ：204205-90-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 204205-90-3 Cat. No. BCP33949
Name Indibulin
Synonyms ZIO 301;D 24851;ZIO301;D24851;ZIO-301;D-24851;
SMILES C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C(=O)C(=O)NC4=CC=NC=C4
Chemical Name
Formula C22H16ClN3O2 M. Wt 389.83
Purity 98% Storage Store at 4-8°C
Description Indibulin is a synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines. Check for active clinical trials or closed clinical trials using this agent.
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