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Denibulin Chemical Structure

Denibulin

Cat. No. :BCP21548CAS No. :284019-34-7Purity:98%
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Synonyms MN029; MN-029; MN 029
CAS Number 284019-34-7
Purity 98%
M. Wt 385.44
Formula C18H19N5O3S
Storage Store at 4-8°C
Denibulin is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. The results of preclinical study demonstrated that MN-029 could cause rapid vascular shutdown in solid tumors, dose-dependent secondary tumor cell killing, and effective enhancement of the antitumor effects of radiation and cisplatin chemotherapy.

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