Pico145

  • Chemical Properties
CAS No. 1628287-16-0 Cat. No. BCP35558
Name Pico145
Synonyms Pico-145; Pico 145; HC-608; HC 608; HC608;
Formula C23H20ClF3N4O5 M. Wt 524.88
  • Biological Activity
Description Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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