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Pico145 Chemical Structure

Pico145

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35558CAS No. :1628287-16-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1628287-16-0 Cat. No. BCP35558
Name Pico145
Synonyms Pico-145; Pico 145; HC-608; HC 608; HC608;
SMILES ClC1=CC=C(CN2C(C(N(C3=O)CCCO)=O)=C(N=C2OC4=CC=CC(OC(F)(F)F)=C4)N3C)C=C1
Chemical Name
Formula C23H20ClF3N4O5 M. Wt 524.88
Purity 98% Storage Store at 4-8°C
Description Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
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