Pyr3 New
Data Sheet
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| CAS No. | 1160514-60-2 | Cat. No. | BCP42100 |
| Name | Pyr3 | ||
| Synonyms | Pyr-3; Pyr 3; | ||
| SMILES | CCOC(=O)C1=C(N(N=C1)C2=CC=C(C=C2)NC(=O)C(=C(Cl)Cl)Cl)C(F)(F)F | ||
| Chemical Name | |||
| Formula | C16H11Cl3F3N3O3 | M. Wt | 456.63 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pyr3, a pyrazole derivative, is a selective antagonist of the TRP canonical 3 channel (TRPC3) which can function as a receptor-operated channel. It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 μM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05 μM. | ||
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