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GSK2193874 Chemical Structure

GSK2193874

Data Sheet For research use only. Not for human use.
Cat. No. :BCP36070CAS No. :1336960-13-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1336960-13-4 Cat. No. BCP36070
Name GSK2193874
Synonyms GSK 2193874; GSK-2193874; GSK2193874A; GSK 2193874A; GSK-2193874A;
SMILES C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7
Chemical Name
Formula C37H38BrF3N4O M. Wt 691.64
Purity 98% Storage Store at 4-8°C
Description GSK2193874 is a potent antagonist of TRPV4 channels, blocking the influx of calcium induced by the TRPV4 agonist GSK634775 with IC50 values of 2, 5, and 40 nM. It is selective for TRPV4 over ~200 other human receptors, channels, and enzymes.
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