Mechlorethamine hydrochloride
| CAS No. | 55-86-7 | Cat. No. | BCP35605 |
| Name | Mechlorethamine hydrochloride | ||
| Synonyms | Chlormethine hydrochloride; Chlorethamine HCl;Mechlorethamine HCl; | ||
| Formula | C5H12Cl3N | M. Wt | 192.51 |
| Description | Mechlorethamine Hydrochloride is the hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities. Mechlorethamine is metabolized to an unstable, highly reactive ethyleniminium intermediate that alkylates DNA, particularly the 7 nitrogen of guanine residues, resulting in DNA base pair mismatching, DNA interstrand crosslinking, the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis. This agent also exhibits lympholytic properties. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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