LY345899

  • Chemical Properties
CAS No. 10538-99-5 Cat. No. BCP35611
Name LY345899
Synonyms LY-345899; LY 345899;
Formula C20H21N7O7 M. Wt 471.43
  • Biological Activity
Description LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1.
Pathways Others Pathway 
Targets Others 

Structure

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