TIS108

  • Chemical Properties
CAS No. 1315459-30-3 Cat. No. BCP36705
Name TIS108
Synonyms TIS-108;TIS 108;
Formula C20H21N3O2 M. Wt 335.4
  • Biological Activity
Description TIS108 is a triazole-type strigolactone (SL)-biosynthesis inhibitor that reduces the level of 2'-epi-5-deoxystrigol (epi-5DS) in rice. Here we report the effects of TIS108 on Arabidopsis. Treatment of TIS108 increased the number of branches and repressed root hair elongation as was observed in SL-deficient mutants, and co-application of GR24, a synthetic SL analog, recovered the TIS108-induced phenotype to that of wild-type. In addition, MAX3 and MAX4 genes in the SL-biosynthesis pathway were upregulated in TIS108-treated Arabidopsis, probably due to feedback regulation caused by SL deficiency. These results indicate that TIS108 is an effective tool for regulating SL production in Arabidopsis.
Pathways Others Pathway 
Targets Others 

Structure

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