FTI-2153
| CAS No. | 344900-92-1 | Cat. No. | BCP37169 |
| Name | FTI-2153 | ||
| Synonyms | FTI2153; FTI 2153; | ||
| Formula | C25H30N4O3S | M. Wt | 466.60 |
| Description | FTI-2153 is a potent farnesyltransferase inhibitor. FTI-2153 inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. FTI-2153 was reported to block bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FTase | ||
Structure
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