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FTI-2153 Chemical Structure

FTI-2153

Data Sheet For research use only. Not for human use.
Cat. No. :BCP37169CAS No. :344900-92-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 344900-92-1 Cat. No. BCP37169
Name FTI-2153
Synonyms FTI2153; FTI 2153;
SMILES CC1=CC=CC=C1C2=C(C=CC(=C2)CNCC3=CN=CN3)C(=O)NC(CCSC)C(=O)OC
Chemical Name
Formula C25H30N4O3S M. Wt 466.60
Purity 98% Storage Store at 4-8°C
Description FTI-2153 is a potent farnesyltransferase inhibitor. FTI-2153 inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. FTI-2153 was reported to block bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells.
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