2-Methylthioadenosine diphosphate trisodium salt

  • Chemical Properties
CAS No. 475193-31-8 Cat. No. BCP42041
Name 2-Methylthioadenosine diphosphate trisodium salt
Synonyms 2-(Methylthio)adenosine 5'-diphosphate sodium salt;
Formula C11H14N5Na3O10P2S M. Wt 539.24
  • Biological Activity
Description 2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13), which induces platelet aggregation and shape change and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein 
Targets P2 Receptor  

Structure

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