Pax2 inhibitor EG1
CAS No. | 693241-54-2 | Cat. No. | BCP42680 |
Name | Pax2 inhibitor EG1 | ||
Synonyms | EG1; | ||
Formula | C22H18N2O5 | M. Wt | 390.39 |
Description | Pax2 inhibitor EG1 is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM; inhibits Pax2 mediated expression with IC50 of 10 uM, and inhibits proliferation of Pax2 positive renal and ovarian cancer cell lines but has little effect on Pax2 negative cancer cells; inhibits embryonic kidney development. | ||
Pathways | Others Pathway | ||
Targets | Others |
Structure
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