Pax2 inhibitor EG1 New
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For research use only. Not for human use.
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| CAS No. | 693241-54-2 | Cat. No. | BCP42680 |
| Name | Pax2 inhibitor EG1 | ||
| Synonyms | EG1; | ||
| SMILES | COC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)NC3=CC=CC=C3C(=O)O | ||
| Chemical Name | |||
| Formula | C22H18N2O5 | M. Wt | 390.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pax2 inhibitor EG1 is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM; inhibits Pax2 mediated expression with IC50 of 10 uM, and inhibits proliferation of Pax2 positive renal and ovarian cancer cell lines but has little effect on Pax2 negative cancer cells; inhibits embryonic kidney development. | ||
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