SBI-477

  • Chemical Properties
CAS No. 781628-99-7 Cat. No. BCP42957
Name SBI-477
Synonyms SBI 477; SBI477;
Formula C24H25N3O6S M. Wt 483.54
  • Biological Activity
Description SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 inhibited triacylglyceride (TAG) synthesis and enhanced basal glucose uptake in human skeletal myocytes. SBI-477 stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4).
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets IGF1R 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.