SBI-477 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 781628-99-7 | Cat. No. | BCP42957 |
| Name | SBI-477 | ||
| Synonyms | SBI 477; SBI477; | ||
| SMILES | COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC(=C(C=C3)OCC(=O)N4CCOCC4)OC | ||
| Chemical Name | |||
| Formula | C24H25N3O6S | M. Wt | 483.54 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 inhibited triacylglyceride (TAG) synthesis and enhanced basal glucose uptake in human skeletal myocytes. SBI-477 stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). | ||
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