NT-157 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1384426-12-3 | Cat. No. | BCP29982 |
| Name | NT-157 | ||
| Synonyms | NT 157; NT157;Tyrphostin NT157;Tyrphostin NT-157; | ||
| SMILES | C1=C(C=C(C(=C1O)O)O)CNC(=CC=C2C=C(C(=O)C(=C2)Br)O)S | ||
| Chemical Name | |||
| Formula | C16H14BrNO5S | M. Wt | 412.26 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | NT157 is a selective inhibitor of IRS-1/2. NT157 significantly affected the cells' migratory ability. NT-157 induced cytostatic effects, as evidenced by G2/M cell cycle arrest, and did not affect apoptosis. NT157 has the potential to inhibit IGF-1R and STAT3 signaling pathways in cancer cells and stroma cells of TME leading to a decrease in cancer cell survival. | ||
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