Home   >  
Angiogenesis/Protein Tyrosine Kinase
  • PI3K/Akt/mTOR
  • Wnt/Stem Cell
∨
  >  
IGF1R
  • GSK3
∨
  >   NVP-ADW742
NVP-ADW742 Chemical Structure

NVP-ADW742

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01826CAS No. ：475488-23-4Purity：98%
chem_1Get Quotation Now
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Chemical Properties&Biological Activity
CAS No. 475488-23-4 Cat. No. BCP01826
Name NVP-ADW742
Synonyms ADW; NVP ADW-742; NVP ADW 742; ADW 742; ADW-742; ADW742; GSK 552602A; GSK-552602A; GSK552602A;
SMILES
Chemical Name
Formula C28H31N5O M. Wt 453.58
Purity 98% Storage Store at 4-8°C
Description NVP-ADW742, also known as ADW-742 or GSK 552602A, is a novel small weight molecular inhibitor of IGF-IR with potential anticancer activity. NVP-ADW742 inhibited IGF-IR-mediated proliferation with an IC50 of 11.12 µmol/l. NVP-ADW742 induced early suppression of Akt, P38 and GSK-3β phosphorylation. NVP-ADW742 enhanced the chemosensitivity of Daoy to temozolomide in vitro, as a potent anti-tumor agent highly selective against IGF-IR. NVP-ADW742 was found to suppresse survival and resistance to chemotherapy in acute myeloid leukemia cells.
  • Quality Control&Technical Support
LCMS H-NMR
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:NVP-ADW742 supplier,NVP-ADW742 purchase,NVP-ADW742 manufacturer,NVP-ADW742 distributor,NVP-ADW742 cost,NVP-ADW742 buy,NVP-ADW742 for sale

0086-13720134139