AZ10606120 dihydrochloride

  • Chemical Properties
CAS No. 607378-18-7 Cat. No. BCP43716
Name AZ10606120 dihydrochloride
Synonyms AZ 10606120 Dihydrochloride;AZ10606120 2HCl;
Formula C25H36Cl2N4O2 M. Wt 495.49
  • Biological Activity
Description AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein 
Targets P2 Receptor  

Structure

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