BIIB068
| CAS No. | 1798787-27-5 | Cat. No. | BCP44097 |
| Name | BIIB068 | ||
| Synonyms | BIIB 068; BIIB-068; | ||
| Formula | C23H29N7O2 | M. Wt | 435.52 |
| Description | BIIB068 is a potent, selective, reversible and orally active BTK inhibitor. BIIB068 demonstrated good kinome selectivity with good overall drug-like properties for oral dosing, was well tolerated across preclinical species at pharmacologically relevant doses with good ADME properties, and achieved >90% inhibition of BTK phosphorylation (pBTK) in humans. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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