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BIIB068 Chemical Structure

BIIB068

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP44097CAS No. ：1798787-27-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1798787-27-5 Cat. No. BCP44097
Name BIIB068
Synonyms BIIB 068; BIIB-068;
SMILES CC1=C(C=CC(=C1)C2=NC(=NC=C2)NC3=CN(N=C3)C)CNC(=O)N4CC(C4)OC(C)C
Chemical Name
Formula C23H29N7O2 M. Wt 435.52
Purity 98% Storage Store at 4-8°C
Description BIIB068 is a potent, selective, reversible and orally active BTK inhibitor. BIIB068 demonstrated good kinome selectivity with good overall drug-like properties for oral dosing, was well tolerated across preclinical species at pharmacologically relevant doses with good ADME properties, and achieved >90% inhibition of BTK phosphorylation (pBTK) in humans.
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