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Orelabrutinib Chemical Structure

Orelabrutinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP37603CAS No. :1655504-04-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1655504-04-3 Cat. No. BCP37603
Name Orelabrutinib
Synonyms ICP-022; ICP022; ICP 022;
SMILES C=CC(=O)N1CCC(CC1)C2=NC(=C(C=C2)C(=O)N)C3=CC=C(C=C3)OC4=CC=CC=C4
Chemical Name
Formula C26H25N3O3 M. Wt 427.50
Purity 98% Storage Store at 4-8°C
Description Orelabrutinib is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK.
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