Maralixibat bromide

  • Chemical Properties
CAS No. 228113-66-4 Cat. No. BCP44157
Name Maralixibat bromide
Synonyms LUM-001; LUM 001; LUM001; SHP625; SHP-625; SHP 625;
Formula C40H56ClN3O4S M. Wt 710.42
  • Biological Activity
Description Maralixibat is an ileal bile acid transporter inhibitor, like odevixibat. Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome, who are at least 1 year old. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and sertraline alone or in combination.
Pathways Others Pathway 
Targets Others 

Structure

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