Maralixibat bromide New
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CAS No. | 228113-66-4 | Cat. No. | BCP44157 |
Name | Maralixibat bromide | ||
Synonyms | LUM-001; LUM 001; LUM001; SHP625; SHP-625; SHP 625; | ||
SMILES | CCCCC1(CS(=O)(=O)C2=C(C=C(C=C2)N(C)C)C(C1O)C3=CC=C(C=C3)OCC4=CC=C(C=C4)C[N+]56CCN(CC5)CC6)CCCC.[Cl-] | ||
Chemical Name | |||
Formula | C40H56ClN3O4S | M. Wt | 710.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Maralixibat is an ileal bile acid transporter inhibitor, like odevixibat. Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome, who are at least 1 year old. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and sertraline alone or in combination. |
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