PHPS1

  • Chemical Properties
CAS No. 314291-83-3 Cat. No. BCP44181
Name PHPS1
Synonyms PHPS 1; PHPS-1;
Formula C21H15N5O6S M. Wt 465.44
  • Biological Activity
Description PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.
Pathways Protease/Metabolic Enzyme 
Targets Phosphatase 

Structure

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