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PHPS1 Chemical Structure

PHPS1

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP44181CAS No. ：314291-83-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 314291-83-3 Cat. No. BCP44181
Name PHPS1
Synonyms PHPS 1; PHPS-1;
SMILES C1=CC=C(C=C1)N2C(=O)C(=C(N2)C3=CC=C(C=C3)[N+](=O)[O-])N=NC4=CC=C(C=C4)S(=O)(=O)O
Chemical Name
Formula C21H15N5O6S M. Wt 465.44
Purity 98% Storage Store at 4-8°C
Description PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.
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