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Trodusquemine Chemical Structure

Trodusquemine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44501CAS No. :186139-09-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 186139-09-3 Cat. No. BCP44501
Name Trodusquemine
Synonyms MSI-1436; MSI1436; MSI 1436; MSI-1436C; MSI1436C; MSI 1436C; Aminosterol 1436; Aminosterol1436; Aminosterol-1436;
SMILES CC(C)C(CCC(C)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)NCCCNCCCCNCCCN)C)O)C)OS(=O)(=O)O
Chemical Name
Formula C37H72N4O5S M. Wt 685.07
Purity 98% Storage Store at 4-8°C
Description Trodusquemine is a protein tyrosine phosphatase PTP-1B inhibitor potentially for the treatment of type 2 diabetes. Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue in vivo.
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