Trodusquemine
| CAS No. | 186139-09-3 | Cat. No. | BCP44501 |
| Name | Trodusquemine | ||
| Synonyms | MSI-1436; MSI1436; MSI 1436; MSI-1436C; MSI1436C; MSI 1436C; Aminosterol 1436; Aminosterol1436; Aminosterol-1436; | ||
| Formula | C37H72N4O5S | M. Wt | 685.07 |
| Description | Trodusquemine is a protein tyrosine phosphatase PTP-1B inhibitor potentially for the treatment of type 2 diabetes. Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue in vivo. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphatase | ||
Structure
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