Lu AF27139
| CAS No. | 2097117-06-9 | Cat. No. | BCP44190 |
| Name | Lu AF27139 | ||
| Synonyms | LuAF27139; Lu-AF27139; | ||
| Formula | C21H19ClF3N5O2S | M. Wt | 497.92 |
| Description | Lu AF27139 is a novel rodent-active and CNS penetrant P2X7 receptor antagonist. Lu AF27139 is highly selective and potent against rat, mouse, and human forms of the receptors. The rat pharmacokinetic profile is favorable with high oral bioavailability, modest clearance (0.79 L/(h kg)), and good CNS permeability. Lu AF27139 will be a valuable tool for probing the role of the P2X7 receptor in rodent models of CNS diseases. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | P2 Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.