DUBs-IN-2

  • Chemical Properties
CAS No. 924296-19-5 Cat. No. BCP46476
Name DUBs-IN-2
Synonyms DUB-IN-2;
Formula C15H9N5O M. Wt 275.26
  • Biological Activity
Description DUBs-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8.In Vitro:DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM.
Pathways Cell Cycle/DNA Damage 
Targets DUB 

Structure

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