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DUBs-IN-2 Chemical Structure

DUBs-IN-2

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46476CAS No. :924296-19-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 924296-19-5 Cat. No. BCP46476
Name DUBs-IN-2
Synonyms DUB-IN-2;
SMILES CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N
Chemical Name
Formula C15H9N5O M. Wt 275.26
Purity 98% Storage Store at 4-8°C
Description DUBs-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8.In Vitro:DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM.
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