(R)-Talarozole
CAS No. | 870093-23-5 | Cat. No. | BCP21218 |
Name | (R)-Talarozole | ||
Synonyms | Talarozole R enantiomer;R115866;R 115866;R-115866; | ||
Formula | C21H23N5S | M. Wt | 377.51 |
Description | Talarozole is a CYP26 inhibitor under development for the treatment of acne, psoriasis and other keratinization disorders. Talarozole inhibits the metabolism of retinoic acid by blocking the cytochrome P450 enzyme isoform CYP26, a retinoic acid hydroxylase. Because of this mechanism, it is called a retinoic acid metabolism blocking agent (RAMBA). | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | Cytochrome P450 |
Structure
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