(R)-Talarozole New
Data Sheet
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| CAS No. | 870093-23-5 | Cat. No. | BCP21218 |
| Name | (R)-Talarozole | ||
| Synonyms | Talarozole R enantiomer;R115866;R 115866;R-115866; | ||
| SMILES | CCC(CC)C(C1=CC=C(C=C1)NC2=NC3=CC=CC=C3S2)N4C=NC=N4 | ||
| Chemical Name | |||
| Formula | C21H23N5S | M. Wt | 377.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Talarozole is a CYP26 inhibitor under development for the treatment of acne, psoriasis and other keratinization disorders. Talarozole inhibits the metabolism of retinoic acid by blocking the cytochrome P450 enzyme isoform CYP26, a retinoic acid hydroxylase. Because of this mechanism, it is called a retinoic acid metabolism blocking agent (RAMBA). | ||
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