Rivoglitazone

  • Chemical Properties
CAS No. 185428-18-6 Cat. No. BCP06166
Name Rivoglitazone
Synonyms CI-1037; CI 1037; CI1037; CS-011; CS011; CS011; DE-101; R-119702;
Formula C20H19N3O4S M. Wt 397.45
  • Biological Activity
Description Rivoglitazone is a peroxisome proliferator-activated receptor γ agonist (PARPγ agonist) potentially for the treatment of type 2 diabetes. Rivoglitazone has been shown, through small clinical studies, to decrease hemoglobin A(1c) (A1C) by 0.11-1.1% when compared with placebo and may provide greater A1C reduction than pioglitazone. Rivoglitazone reduces hyperglycemia, hyperinsulinemia, and hypertriglyceridemia by acting as an agonist of PPAR-γ. Rivoglitazone is the most potent PPAR-γ agonist.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets PARP 

Structure

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