Bleomycin Sulphate

  • Chemical Properties
CAS No. 9041-93-4 Cat. No. BCP01387
Name Bleomycin Sulphate
Synonyms BLEO; BLM; BLEO cell; BLEO-cell; BLEOcell; Bleolem;
Formula C55H85N17O25S4 M. Wt 1512.62
  • Biological Activity
Description Bleomycin sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.
Related Products 11056-06-7(Bleomycin) 67763-87-5(Bleomycin hydrochloride)
Pathways Microbiology/Virology Cell Cycle/DNA Damage 
Targets DNA/RNA Synthesis Antibiotic 

Structure

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