SD208
| CAS No. | 627536-09-8 | Cat. No. | BCP02214 |
| Name | SD208 | ||
| Synonyms | SD-208;SD208;TGF-β RI Kinase Inhibitor V; | ||
| Formula | C17H10ClFN6 | M. Wt | 352.75 |
| Description | Studies indicate that TGF-βRI Kinase Inhibitor V reduces the number of myofibroblasts at fibroblastic foci. In addition, this compound is effective in blocking autocrine and paracrine TGF-β signaling in glioma cells and restores the lytic activity of polyclonal natural killer cells against glioma cells. This inhibitor functions in suppressing the action of MAPKAP and PKD. | ||
| Pathways | TGF beta/Smad Wnt/Stem Cell | ||
| Targets | BMP/TGF beta Receptor TGF β/Smad | ||
Structure
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