NU 1025
| CAS No. | 90417-38-2 | Cat. No. | BCP27646 |
| Name | NU 1025 | ||
| Synonyms | NU-1025;NU1025; | ||
| Formula | C9H8N2O2 | M. Wt | 176.17 |
| Description | NU1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1025 enhanced the cytotoxicity of the DNA-methylating agent MTIC, gamma-irradiation and bleomycin 3.5-, 1.4- and 2-fold respectively. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
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