UNC2250
| CAS No. | 1493694-70-4 | Cat. No. | BCP09929 |
| Name | UNC2250 | ||
| Synonyms | UNC-2250;UNC 2250; | ||
| Formula | C24H36N6O2 | M. Wt | 440.58 |
| Description | UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. Treatment with UNC2250 also resulted in decreased colony-forming potential in rhabdoid and NSCLC tumor cells, thereby demonstrating functional antitumor activity. The results provide a rationale for further investigation of UNC2250 for therapeutic application in patients with cancer. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | TAM Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.