BX471

  • Chemical Properties
CAS No. 217645-70-0 Cat. No. BCP10157
Name BX471
Synonyms BX 471;BX-471;ZK-811752;ZK 811752;ZK811752;
Formula C21H24ClFN4O3 M. Wt 434.89
  • Biological Activity
Description BX471 inhibits MIP-α/CCL3-induced intracellular Ca2+ mobilization. BX471 is orally active; effectively reduces disease severity in a rat model of multiple sclerosis. Decreases renal fibrosis in a mouse model of obstructive nephropathy.
Pathways GPCR/G Protein 
Targets CXCR CCR 

Structure

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