Parthenolide
| CAS No. | 20554-84-1 | Cat. No. | BCP10404 |
| Name | Parthenolide | ||
| Synonyms | (-)-Parthenolide; NSC-157035; NSC 157035; NSC157035; | ||
| Formula | C15H20O3 | M. Wt | 248.32 |
| Description | Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition.Parthenolide, a kind of sesquiterpene lactone compound, could be used against ischemic injury as an anti-inflammatory drug and has been found to be effective in inducing apoptosis of cancer cells and eradicate cancer stem cells. | ||
| Pathways | Apoptosis Pathway NFκB | ||
| Targets | NF κB Mdm2 p53 | ||
Structure
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