PKC-IN-1

  • Chemical Properties
CAS No. 1046787-18-1 Cat. No. BCP10410
Name PKC-IN-1
Synonyms
Formula C25H37FN8O2 M. Wt 500.61
  • Biological Activity
Description PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5.3 and 10.4 nM for human PKCβ and PKCα, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε, respectively.
Pathways TGF beta/Smad  Epigenetics 
Targets PKC 

Structure

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