SB-265610
| CAS No. | 211096-49-0 | Cat. No. | BCP28242 |
| Name | SB-265610 | ||
| Synonyms | SB 265610; SB265610; | ||
| Formula | C14H9BrN6O | M. Wt | 357.17 |
| Description | SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CXCR | ||
Structure
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