Fluralaner

  • Chemical Properties
CAS No. 864731-61-3 Cat. No. BCP23785
Name Fluralaner
Synonyms AH252723; AH-252723; AH 252723; A-1443; A1443; A 1443;
Formula C22H17Cl2F6N3O3 M. Wt 556.29
  • Biological Activity
Description Fluralaner, also known as AH252723, is a systemic insecticide and acaricide that is administered orally. The US Food and Drug Administration (FDA) approved it under the trade name Bravecto for flea treatment in dogs in May 2014. The EU approved the drug in February 2014. Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls).
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway Microbiology/Virology 
Targets Antiparasitics GABA Receptor 

Structure

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