Darbufelone mesylate

  • Chemical Properties
CAS No. 139340-56-0 Cat. No. BCP23976
Name Darbufelone mesylate
Synonyms CI-1004 mesylate;Darbufelone mesilate;CI1004 mesylate;CI 1004 mesylate;
Formula C18H24N2O2S.CH4O3S M. Wt 428.57
  • Biological Activity
Description Darbufelone mesylate is a dual inhibitor of cellular prostaglandin and leukotriene production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM).
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Prostaglandin Receptor Leukotriene Receptor COX 

Structure

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